Scale-up/scale-down device for
development of tangential flow filtration
(TFF) processes, biopharmaceutical
small batch production, scale-down
investigations, and production of
materials for safety and efficacy
studies (Phase I clinicals).
Identical path lengths provide linear
scale-up to Pall Centramate and
Centrasette™ cassette holders.
The LV Centramate holder may be
attached to other laboratory TFF
systems to improve their scalability
Low hold-up volume allows high
concentration factors to be achieved
from small starting volumes. A
complete TFF system scalable to full
production plant can be optimized
using the volumes typically generated
in the development or discovery lab.
Easy connections through luer lock
fitted ports with polished 316L
stainless steel to ensure the same
compatibility characteristics as
production-scale Centrasette holders.
All product-wetted parts comply with
Plug-n-play design. Plug in a
Minimate TFF capsule, add sample,
and turn on the pump to start
processing. The Minimate TFF
system includes all the hardware,
tubing, and fittings needed to get
your TFF process up and running
High concentration factors. The low
system working volume achieved
through the use of a conical bottom
reservoir and compact design
enables high concentration factors
from up to 1 L or more of sample to
be achieved. Concentrate your
sample down to as little as 5 mL.
All wetted components are made
from low protein binding, chemically
resistant, biologically safe materials.